| Seasonal Affective Disorder (SAD), or
"Winter Depression," as it is also known, afflicts large numbers of Americans during the months of
November through March. Various estimates place the actual figure at anywhere from 10 to more than
65 million people suffering from SAD at some point during their lives.
What is SAD?
SAD is a recurring prolonged period of depression, whose onset and remission coincides with
changes in the seasons. In most cases the depression begins in late fall or early winter and
persists until spring or sometimes even into summer. Slightly more women than men report suffering
from SAD, and the majority of those afflicted with SAD are under the age of 40.
According to Dr. Kathleen B. Speicher of the Student Health Center, Indiana University—Purdue
University Indianapolis, the common symptoms of SAD include "a change in appetite (especially a
craving for sweet or starchy foods), weight gain, a heavy feeling in the arms and legs, a drop in
energy level, fatigue, a tendency to oversleep, difficulty concentrating, irritability, increased
sensitivity to social rejection and avoidance of social situations (hibernation)."
Some scientists believe that it is not so much the reduced number of daylight hours which
promotes the onset of SAD, but rather the winter sunlight itself being less intense, often further
diffused by heavy cloud cover. Others theorize that waking up on winter mornings prior to sunrise
upsets the body's internal "clock," which is believed to be "synchronized" to local time through
exposure to morning daylight. Still other researchers suggest that SAD may actually be the result of
a combination of these effects, or even other effects that have not yet been identified.
Light Therapy for SAD Sufferers
About 20 years ago, it was first demonstrated that exposing humans to high-intensity light could
actually bring about positive changes in the brain chemistry and help to counteract feelings of
depression. So it was theorized that exposing people to increased amounts of intense light in the
wintertime might have a similar beneficial effect upon those suffering from winter depression. And
subsequent research has conclusively proved that light therapy does indeed significantly help many
who suffer from SAD.
One study, reported in the Archives of General Psychiatry (October, 1998), was conducted
by Dr. Charmane Eastman of Rush-Presbyterian St. Luke's Medical Center in Chicago. According to a
report of her study on ABC News, "61 percent of people who got morning light therapy and 50 percent
of people who got evening light therapy experienced nearly complete recovery from their seasonal
depression after four weeks of treatment."
Another prominent researcher, Dr. Raymond W. Lam, described the current recommended procedure for
administering light therapy in the October 2002 issue of Psychiatric Times. "The recommended
protocol for light treatment," he explained, "is 10,000 lux exposure, administered by a fluorescent
light box with an ultraviolet filter, for at least 30 minutes per day in the early morning (Lam and
Levitt, 1999). Less intense light usually requires greater duration of exposure for the same
response, e.g., 3,000 lux for one to two hours." Dr. Lam commented that improvement is often noted
after only one week, with most patients noticing improvement within 2 to 4 weeks. Patients generally
suffer relapse after the treatments are stopped, so they must be continued until the time of year
when the symptoms of SAD would otherwise have subsided without light therapy.
Commenting on several recent clinical studies of light therapy for SAD, Dr. Anna Wirz-Justice, of
the Psychiatric University Clinic in Basel, Switzerland, wrote in an editorial in the October, 1998
issue of the Archives of General Psychiatry, "Light is as effective as drugs, perhaps more
so." She went on to comment, "Light is an effective antidepressant in seasonal affective disorder
(SAD)... Light therapy is easy to administer in out patient settings, lacks major side effects, and,
importantly, is cost effective."
(Continued at top of next column)
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Negative
Ionization—Another Promising Therapy
Another promising new line of research involves the treatment of SAD by exposure to high-density
negative ions. Negative ions are negatively charged molecules of air that occur naturally in the
environment. Winter air generally contains a far lower concentration of negative ions than summer
air. There is also evidence to suggest that the concentration of negative ions in the air may have
an effect on serotonin levels in the brain. So it seemed reasonable to a number of researchers that
enhancing the amount of negative ions in the air might also have a beneficial effect on winter
depression.
Dr. Charmane Eastman, in her study of the effects of light on SAD (mentioned above), used a
nonfunctioning negative ion generator as a placebo for her control group. Intrigued by this,
Drs. Michael Terman and Jiuan Su Terman, psychiatrists at Columbia University in New York, decided
to actually test the effect of negative ions on individuals suffering from SAD
using a fully functional generator. Their double-blind, controlled
test of low-density (10,000 ions per cubic centimeter) against high-density (2,700,000 ions per
cubic centimeter) negative ion treatment made a surprising discovery.
As reported in the January, 1995 issue of the Journal of Alternative and Complementary
Medicine, 58% of those in the Terman study receiving the high-density negative ion treatment
reported that symptoms of winter depression were actually reduced by 50% or more without any
side-effects. The researchers concluded that "treatment with a high-density negative ionizer appears
to act as a specific antidepressant for patients with seasonal affective disorder. The method may be
useful as an alternative or supplement to light therapy and medications."
In a follow-up study by the Termans, according to an October 14th, 1998 report by
ABC News, they "compared light therapy to treatment with high- or low-density negative ion
emitters." The Termans "found that light-therapy patients did 30 percent better than those who got
the low-density ions. Patients who got high-density ions did just as well as light-therapy patients,
indicating that the high-dose ions might also be helpful in treating SAD."
A Columbia University spokesperson summarizes what has been learned so far about negative ions as
a treatment for SAD. "Summer air, in contrast to winter air, is highly concentrated with negative
ions. The negative ion machines we use are designed to mimic summer-like conditions by supplementing
the sparse winter ion supply. We are finding that this evokes beneficial mood effects. Although the
ions emitted from the machines are not perceptible to your senses, studies have indicated clear
improvement in patients with winter depression."
Further Research Needed
There is still much yet to be learned about the connection between SAD, light and negative ions.
What is the optimum intensity vs. duration vs. time of exposure to light for best results in
attempting to treat SAD? Why does exposure to high-density negative ions seem to be about as
effective as light therapy? What concentration of negative ions would be optimum? What about
combining both light and negative ion therapies to treat SAD, and in what proportions? The full
answers to these questions are not yet known. It is therefore a field that researchers are
continuing to actively investigate.
Comtech Research offers
high-density negative ionizers
for purchase online here.

Not a medical device.
See the disclaimer
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